Author

S. Tighe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

A. L. Greninger· 1 shared A. Nalla· 1 shared B. D. Kirkpatrick· 1 shared C. D. Huston· 1 shared D. G. B. Leonard· 1 shared D. Ionescu· 1 shared D. J. Shirley· 1 shared D. L. Gerrard· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMicrobiology

A. L. Greninger

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cave Thiovulaceae differ metabolically and genomically from marine species

M. Bizic, T. Brad, D. Ionescu, L. Barbu-Tudoran, J. Aerts, R. Popa, L. Zoccarato, J. Ody, J.-F. Flot, S. Tighe, D. Vellone, S. M. Sarbu

The paper compares the genomes of cave-dwelling Thiovulum species to a marine strain, revealing metabolic adaptations for sulfur and nitrogen cycling in subterranean environments.

bioRxiv · Nov 4, 2020 · PreprintMicrobiology

DIRECT RT-qPCR DETECTION OF SARS-CoV-2 RNA FROM PATIENT NASOPHARYNGEAL SWABS WITHOUT AN RNA EXTRACTION STEP

E. A. Bruce, M.-L. Huang, G. A. Perchetti, S. Tighe, J. J. Hoffman, P. Laaguiby, D. L. Gerrard, A. Nalla, Y. Wei, A. L. Greninger, S. A. Diehl, D. J. Shirley, D. G. B. Leonard, C. D. Huston, B. D. Kirkpatrick, , J. W. Botten

This paper tests a direct RT-qPCR method for detecting SARS-CoV-2 RNA in nasal swabs without RNA extraction, achieving 92% accuracy on blinded samples.

bioRxiv · Mar 20, 2020Microbiology