A co-opted endogenous retroviral envelope promotes cell survival by controlling SLC31A1/CTR1-mediated copper transport and homeostasis
S. Tury, L. Chauveau, V. Courgnaud, J.-L. Battini
The paper identifies Refrex1, an endogenous retroviral envelope protein, as a regulator of copper homeostasis through interaction with SLC31A1/CTR1, demonstrating its role in cell survival by controlling copper levels and redox balance.
bioRxiv · Dec 9, 2021Microbiology