Twist, Snail, and Sox9 form an allosterically regulated complex, the EMTosome, on a bipartite E-box site.
D. McCracken, H. P. Peng, K. Ayyanathan, Y. L. Jiang, S. Welsh, J. Yang, E. Kennedy, F. J. Rauscher, A. Gardini, F. J. Rauscher
The paper identifies a ternary complex, EMTosome, formed by Twist, Snail, and Sox9 that allosterically regulates Twist DNA binding during EMT.
bioRxiv · Feb 3, 2020 · PreprintCancer Biology