AKT regulates mitotic progression of mammalian cells by phosphorylating MASTL
Irfana Reshi, Misbah Un Nisa, Umer Farooq, Syed Qaaifah Gillani, Sameer Ahmad Bhat, Zarka Sarwar, Khalid Majid Fazili, Shaida Andrabi
This study identifies AKT as a regulator of mitosis by phosphorylating MASTL at T299, enhancing its activation and promoting cell proliferation in colorectal cancer.
bioRxiv · Jul 24, 2018 · PreprintCancer Biology