DNA methylation subtypes inferred from transcriptomes guide sunitinib and immunotherapy selection in renal cancer
Florian Jeanneret, Sarah Schoch, Pedro J. Ballester, Stefan Nicholas Symeonides, Alexander Laird, Håkan Axelson, Delphine Pflieger, Christophe Battail
The paper identifies DNA methylation subtypes from transcriptomes to guide sunitinib and immunotherapy selection in renal cancer, finding hyper-methylated tumors respond better to atezolizumab plus bevacizumab.
bioRxiv · Nov 5, 2024 · PreprintBioinformatics