Improving fold activation of small transcription activating RNAs (STARs) with rational RNA engineering strategies.
Sarai Meyer, James Chappell, Sitara Sankar, Rebecca Chew, Julius B Lucks
This paper improves the fold activation of STAR regulators using rational RNA engineering strategies, increasing activation from 5.4-fold to 13.4-fold and demonstrating generalizability across unrelated STARs.
Biotechnology and Bioengineering · Sep 9, 2015Peer-reviewedSynthetic Biology