Author

Sascha Conic

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Làszlò ToraiD· 3 shared Abigail Kora SuwalaiD· 1 shared Agnieszka GambusiD· 1 shared Aleksandra JasiulewicziD· 1 shared Alina HeueriD· 1 shared Amir AbdollahiiD· 1 shared Anton J FaymonvilleiD· 1 shared Atefeh Pourkhalili LangeroudiiD· 1 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersMolecular Biology

Làszlò ToraORCID

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Author profile →

4 papers

Recent·Most cited

RNA polymerase II initiation factors show different dynamic behaviour upon induced transcription in live cells

Attila Oravecz, Olivier Tassy, Sascha Conic, Mustapha Oulad‐Abdelghani, Nacho Molina, Làszlò Tora

The paper investigates the dynamic behavior of RNA polymerase II and its initiation factors during transcription activation in live cells, revealing distinct kinetic behaviors and a quantitative model for PIC assembly.

bioRxiv · Dec 21, 2025 · PreprintMolecular Biology

Characterizing and targeting glioblastoma neuron-tumor networks with retrograde tracing

Svenja Kristin Tetzlaff, Ekin Reyhan, Nikolas Layer, C. Peter Bengtson, Alina Heuer, Julian Schroers, Anton J Faymonville, Atefeh Pourkhalili Langeroudi, Nina Drewa, Elijah Keifert, Julia Wagner, Stella Judith Soyka, Marc Cicero Schubert, Nirosan Sivapalan, Rangel Lyubomirov Pramatarov, , Varun Venkataramani

This study uses retrograde tracing to characterize neuron-tumor networks in glioblastoma and shows that targeting these networks can enhance therapeutic outcomes.

Cell · Dec 6, 2024Peer-reviewedCancer Biology

Co-translation drives the assembly of mammalian nuclear multisubunit complexes

Ivanka Kamenova, Pooja Mukherjee, Sascha Conic, Florian Mueller, Farrah El-Saafin, Paul Bardot, Jean‐Marie Garnier, Doulaye Dembélé, Simona Capponi, H. T. Marc Timmers, Stéphane D. Vincent, Làszlò Tora

The paper shows that mammalian nuclear transcription complexes assemble co-translationally, with dimerization domains dictating the assembly pathway.

Nature Communications · Apr 15, 2019Peer-reviewedMolecular Biology

A cell cycle-coordinated nuclear compartment for Polymerase II transcription encompasses the earliest gene expression before global genome activation

Yavor Hadzhiev, Haseeb Khalid Qureshi, Lucy Wheatley, Ledean Cooper, Aleksandra Jasiulewicz, Huy V. Nguyen, Joseph W. Wragg, Divyasree Poovathumkadavil, Sascha Conic, Sarah Bajan, Attila Gabor SIK, György Hutvágner, Làszlò Tora, Agnieszka Gambus, John Fossey, Ferenc Müller

The paper identifies a nuclear transcription compartment that enables early gene expression before genome activation in metazoan embryos.

Nature Communications · Feb 11, 2019Peer-reviewedDevelopmental Biology