Author

Sebastian Bonhoeffer

Primary ORCID profile (0000-0001-8052-3925 · 11 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Sebastian BonhoefferiD11 papers · ETH Zurich

Biology Disciplines

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Epidemiology· 1 Evolutionary Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:benchmarking· 1 Organism:human· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Gabriel E Leventhal· 1 shared Helen Alexander· 1 shared Nathanael Hoze· 1 shared Roland Regoes· 1 shared Stephanie I. Mayer· 1 shared

Activity by Year

2016-2016 · peak 3/yr

Co-Author Collaboration Network

5 top collaborators · 2 mutual co-author links

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1 shared paperEvolutionary Biology

Gabriel E Leventhal

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3 papers

Recent·Most cited

Assessing the public health impact of tolerance-based therapies with mathematical models

Nathanael Hoze, Sebastian Bonhoeffer, Roland Regoes

This study uses mathematical models to show that tolerance-based therapies may increase disease prevalence and mortality, outperforming conventional treatments in public health outcomes.

bioRxiv · Sep 8, 2016Epidemiology

Potential pitfalls in estimating viral load heritability

Gabriel E Leventhal, Sebastian Bonhoeffer

The paper identifies methodological differences as the source of discrepancies in SPVL heritability estimates and warns against over-reliance on phylogenetic models.

Trends in Microbiology · Sep 1, 2016Peer-reviewedEvolutionary Biology

Population heterogeneity in mutation rate increases mean fitness and the frequency of higher order mutants

Helen Alexander, Stephanie I. Mayer, Sebastian Bonhoeffer

bioRxiv · Mar 30, 2016Genetics