Estimating driver-tissues by robust selective expression of genes associated with complex diseases or traits
Lin Jiang, Chao Xue, Shangzhen Chen, Sheng Dai, Peikai Chen, Pak Chung Sham, Haijun Wang, Miaoxin Li
This paper introduces a framework to estimate driver tissues of complex diseases by analyzing selective gene expression from GWAS data, finding lung as a driver tissue for rheumatoid arthritis.
Genome biology · Nov 6, 2019Peer-reviewedGenetics