A novel approach to digital characterisation of Tertiary Lymphoid Structures in colorectal cancer
Luis Munoz‐Erazo, Saem Mul Park, Shelly Lin, Chun‐Jen J. Chen, Lisa Y. Y. Zhou, Janet L Rhodes, Taesung Jeon, Sonya Fenton, John L McCall, Roslyn A. Kemp, P. Rod Dunbar
This study uses whole-slide digital analysis of multiplexed immunofluorescence images to quantify TLS immune activity in CRC, showing it is more efficient and reveals strong correlations between B-cell and T-cell proliferation.
Frontiers in Immunology · Jan 28, 2025Peer-reviewedCancer Biology