Author

Shirly J

Rajiv Gandhi Centre for Biotechnology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Amrutha Nisthul A.· 1 shared Archana Praveen· 1 shared Arun (Geetha) ViswanathaniD· 1 shared Chenicheri Kizhakkeveettil KeerthanaiD· 1 shared Chittalakkottu SadasivaniD· 1 shared Jayasekharan S. Aparna· 1 shared Kalimuthu Kalishwaralal· 1 shared Kuzhuvelil B. HarikumariD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Amrutha Nisthul A.

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Uttroside B, a US FDA-designated Orphan drug, mitigates thedevelopment of hepatocellular carcinoma and its pulmonary metastasis via EGFR/ERK-mediated inhibition of SREBP-1 and STAT-3

Chenicheri Kizhakkeveettil Keerthana, Tennyson Prakash Rayginia, Kalimuthu Kalishwaralal, Sandhini Saha, Nair Hariprasad Haritha, Amrutha Nisthul A., Mundanattu Swetha, Sreekumar Usha Devi Aiswarya, Lekshmi R. Nath, Sanjay Suresh Varma, Arun (Geetha) Viswanathan, Somaraj Jannet, Shirly J, Jayasekharan S. Aparna, Archana Praveen, , Ruby John Anto

This study shows that Uttroside B inhibits hepatocellular carcinoma and its pulmonary metastasis by blocking the EGFR/ERK pathway and its downstream targets SREBP-1 and STAT-3.

Cell Death Discovery · Apr 16, 2026Peer-reviewedCancer Biology