Activation of Multiple Signalling Pathways by P152Lp53 Mutant Reveals New Gain-of-function Implicating Tumorigenesis
Siddharth Singh, Manoj Kumar, Sanjeev Kumar, Shrinka Sen, Pawan Upadhyay, M Naveen, Vivek S. Tomar, Amit Dutt, Tapas K. Kundu
This study identifies P152Lp53 as a gain-of-function mutant that promotes cell mobility, proliferation, invasion, and tumorigenesis through upregulated signalling pathways.
bioRxiv · Nov 20, 2018 · PreprintCancer Biology