Author

Simone B. Larsen

University of Luxembourg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Bruno F. R. SantosiD· 3 shared Peter A. BarbutiiD· 3 shared Rejko KrügeriD· 3 shared Clara Berenguer-Escuder· 2 shared Dajana GroßmanniD· 2 shared Nobutaka HattoriiD· 2 shared Paul M. A. AntonyiD· 2 shared Aidos BaumuratoviD· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersNeuroscience

Bruno F. R. SantosORCID

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Author profile →

3 papers

Recent·Most cited

The Role of Alpha Synuclein in Synucleinopathy: Impact on Lipid Regulation at Mitochondria ER Membranes

Peter A. Barbuti, Cristina Guardia‐Laguarta, Taekyung Yun, Zena K. Chatila, Xena E. Flowers, Chantel Wong, Bruno F. R. Santos, Simone B. Larsen, James S. Lotti, Nobutaka Hattori, Elizabeth M. Bradshaw, Ulf Dettmer, Saranna Fanning, Vilas Menon, Hasini Reddy, , Serge Przedborski

This paper investigates the role of alpha-synuclein in lipid regulation at MAM domains in synucleinopathies, showing disease-specific lipid alterations and Syn's impact on phosphatidylserine metabolism.

npj Parkinson s Disease · Apr 30, 2025Peer-reviewedNeuroscience

Mitochondria-mitochondria interaction networks show altered topological patterns in Parkinson's disease

Massimiliano Zanin, Bruno F. R. Santos, Paul M. A. Antony, Clara Berenguer-Escuder, Simone B. Larsen, Zoé Hanss, Peter A. Barbuti, Aidos Baumuratov, Dajana Großmann, Christophe Capelle, Joseph Weber, Rudi Balling, Markus W. Ollert, Rejko Krüger, Nico J. Diederich, Feng Q. HeFeng

The paper analyzes mitochondria-mitochondria interaction networks in Parkinson's disease and finds altered topological patterns that correlate with clinical scores and can distinguish patients from controls.

npj Systems Biology and Applications · Nov 10, 2020Peer-reviewedNeuroscience

IPSC-derived midbrain astrocytes from Parkinson's disease patients carrying pathogenic SNCA mutations exhibit alpha-synuclein aggregation, mitochondrial fragmentation and excess calcium release

Peter A. Barbuti, Paul M. A. Antony, Gabriella Novak, Simone B. Larsen, Clara Berenguer-Escuder, Bruno F. R. Santos, François Massart, Dajana Großmann, Takahiro Shiga, Kei‐ichi Ishikawa, Wado Akamatsu, Steven M. Finkbeiner, Nobutaka Hattori, Rejko Krüger

bioRxiv · Apr 27, 2020 · PreprintNeuroscience