SARS-CoV-2 Infects Peripheral Sensory Neurons and Promotes Axonal Degeneration via TRPV1 Activation
Vanessa Anna Co, Siwen Liu, Rachel Chun-Yee Tam, Bobo Wing-Yee Mok, Honglin Chen, Yiling Hong
This study shows SARS-CoV-2 infects sensory neurons via ACE2 and TRPV1, causing axonal damage, and that TRPV1 antagonists can protect neurons.
bioRxiv · Mar 6, 2025 · PreprintCell Biology