Combined celecoxib and NDGA induces a non-canonical, autophagy-independent redox cell death via p62/KEAP1 in colorectal cancer
Rajesh Yadala, Sharvani Palakurthy, Smita Pawar
This study shows that combining celecoxib and NDGA causes redox-mediated cell death in colorectal cancer cells through the p62/KEAP1 axis, independent of autophagy and apoptotic pathways.
bioRxiv · Oct 8, 2026 · PreprintCancer Biology