Author

Sofia Haug

Whitehead Institute for Biomedical Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:protein structure· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:multiome· 1 Research Focus:protein design· 1

Frequent Co-Authors

Iain M. CheesemaniD· 3 shared Ekaterina KhalizevaiD· 2 shared Eric M. SmithiD· 2 shared Jimmy LyiD· 2 shared Sarah L. Cady· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 9 mutual co-author links

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3 shared papersMolecular Biology

Iain M. CheesemanORCID

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3 papers

Recent·Most cited

Translational isoforms of mammalian heterochromatin protein 1 (HP1) tune its interactions with chromatin effectors

Eric M. Smith, Ekaterina Khalizeva, Sofia Haug, Iain M. Cheeseman

The paper shows that mammalian cells produce extended HP1β isoforms that alter effector binding preferences, affecting heterochromatin organization.

bioRxiv · Oct 14, 2026 · PreprintMolecular Biology

SRSF12 is a primate-specific splicing factor that induces a tissue-specific gene expression program

Jimmy Ly, Sarah L. Cady, Sofia Haug, Ekaterina Khalizeva, Iain M. Cheeseman

This study identifies SRSF12 as a primate-specific splicing factor that induces tissue-specific gene expression programs in human cells.

Molecular Biology of the Cell · Oct 8, 2025Peer-reviewedCell Biology

Molecular determinants of RNase MRP specificity and function

Eric M. Smith, Jimmy Ly, Sofia Haug, Iain M. Cheeseman

The paper identifies C18orf21/RMRPP1 as an RNase MRP-specific protein, reveals its role in 40S ribosome biogenesis, and identifies Nepro as an essential rRNA processing factor.

bioRxiv · Jan 28, 2025 · PreprintMolecular Biology