Author

Spencer A. Moritz

University of Washington Bothell

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Molecular Biology· 1

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Approach:deep learning· 1 Assay:electronic health records· 1 Assay:imaging· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:simulation· 1 Research Focus:software / tool· 1

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Dong SiiD· 1 shared Jianlin Jack ChengiD· 1 shared Jie HouiD· 1 shared Jonas PfabiD· 1 shared Liguo WangiD· 1 shared Renzhi CaoiD· 1 shared Tianqi WuiD· 1 shared

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2020-2020 · peak 1/yr

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1 shared paperMolecular Biology

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Recent·Most cited

Molecular BiologyScientific ReportsPeer-reviewedMar 9, 2020

✦ In-depth digest

Cascaded-CNN: Deep Learning to Predict Protein Backbone Structure from High-Resolution Cryo-EM Density Maps

Dong Si, Spencer A. Moritz, Jonas Pfab…·Jianlin Jack Cheng

Cascaded CNNs segmenting secondary structure, backbone and Cα voxels, plus tabu-search tracing, place 88.5% of Cα atoms within 3Å across 50 cryo-EM maps versus Phenix's 66.8%.

108 citationstop 3%

imagingprotein structure