Determination of chemical partitioning in vehicles using a skin surrogate for dermal absorption model refinement.
Ruth U. Pendlington, David Sanders, David Sheffield, Stephen E. Glavin, Hugh Barlow, Hequn Li
The paper measures chemical partitioning in vehicles using a PDMS surrogate to refine a dermal absorption model, improving prediction accuracy for three chemicals.
bioRxiv · May 29, 2025 · PreprintPharmacology & Toxicology