SUV39H1 Preserves Cancer Stem Cell Chromatin State and Properties in Glioblastoma
Chunying Li, Qiqi Xie, Sugata Ghosh, Bihui Cao, Yuanning Du, Vo Van Giau, Timothy Y. Huang, Charles Spruck, Richard L. Carpenter, Yanru Wang, Qing Richard Lu, Kenneth P. Nephew, Jia Shen
This paper shows SUV39H1 is critical for maintaining glioblastoma stem cell properties and progression, and targeting it enhances chemotherapy effectiveness.
JCI Insight · Mar 9, 2025Peer-reviewedCancer Biology