NeurosciencebioRxivPreprint
Fast-acting antidepressants trigger presynaptic BDNF release and structural plasticity at mouse mossy fiber-CA3 synapses
Irem L Atasoy-Rodriguez, Kenneth W. Johnson, Kishan Patel…·Jimcy Platholi
This study shows fast-acting antidepressants like ketamine trigger BDNF release from presynaptic terminals in mouse hippocampal neurons, leading to structural plasticity in CA3 pyramidal neurons.
DOI 10.64898/2026.01.02.697407