Two distinct classes of co-chaperones compete for the EEVD motif in heat shock protein 70 (Hsp70) to tune its activity
O. T. Johnson, C. M. Nadel, E. C. Carroll, T. Arhar, J. E. Gestwicki
The paper identifies two co-chaperones that compete for the EEVD motif of Hsp70, influencing its activity by determining whether bound proteins are folded or degraded.
bioRxiv · Oct 18, 2021 · PreprintBiochemistry