N-linked glycosylation of the M-protein variable region: Glycoproteogenomics reveals a new layer of personalized complexity in multiple myeloma.
P. Langerhorst, M. Baerenfaenger, P. Kulkarni, S. Nadal, C. Wijnands, M. A. Post, S. Noori, M. M. vanDuijn, I. Joosten, T. Dejoie, A. J. van Gool, J. Gloerich, D. J. Lefeber, H. J. Wessels, J. F. M. Jacobs
This study introduces a glycoproteogenomics method to analyze N-glycosylation of M-protein variable regions in multiple myeloma, revealing increased glycan complexity in patient samples compared to healthy controls.
bioRxiv · Apr 5, 2023Cancer Biology