Single nucleus pituitary transcriptomic and epigenetic landscape reveals human stem cell heterogeneity with diverse regulatory mechanisms
Z. Zhang, M. Zamojski, G. R. Smith, T. L. Willis, V. Yianni, N. Mendelev, H. Pincase, N. Seenarine, M. A. S. Amper, M. Vasoya, V. Nair, J. L. Turgeon, D. J. Bernard, O. G. Troyanskaya, C. L. Andoniadou, , F. M. Ruf-Zamojski
The paper characterizes human pituitary stem cells using single nucleus RNA-seq and ATAC-seq, revealing distinct cell types, regulatory mechanisms, and age-related differences.
bioRxiv · Jun 18, 2021 · PreprintCell Biology