Plant PAXX has an XLF-like function and stimulates DNA end-joining by the Ku-DNA ligase IV-XRCC4 complex
The paper identifies a plant PAXX ortholog that functions similarly to human XLF in DNA end-joining by interacting with Ku and XRCC4, suggesting evolutionary merging of PAXX and XLF roles in plants.
bioRxiv · May 26, 2023Plant Biology