The Candida albicans reference strain SC5314 contains a rare, dominant allele of the transcription factor Rob1 that modulates biofilm formation and oral commensalism
V. E. Glazier, J. Kamara, T. Ollinger, N. V. Solis, R. Zarnowski, R. S. Wakade, M.-j. Kim, G. J. Weigel, S.-H. Liang, R. J. Bennett, M. Wellington, D. R. Andes, M. Stamnes, S. G. Filler, D. J. Krysan
This paper identifies a rare, dominant SNP in the Rob1 transcription factor of C. albicans strain SC5314 that enhances biofilm formation and filamentation, contributing to its distinct phenotypic traits.
bioRxiv · Jun 17, 2023 · PreprintMicrobiology