T. Pedron

The Colibactin-Producing Escherichia coli alters the tumor microenvironment to immunosuppressive lipid overload facilitating colorectal cancer progression and chemoresistance.

This study shows that Colibactin-producing Escherichia coli creates an immunosuppressive lipid-rich tumor microenvironment that promotes colorectal cancer progression and chemoresistance.

Parvimonas micra, an oral pathobiont associated with colorectal cancer, epigenetically reprograms human primary intestinal epithelial cells

This study shows that Parvimonas micra phylotype A alters DNA methylation and gene expression in intestinal epithelial cells, potentially contributing to colorectal cancer.