Modelling Porcine NAFLD by Deletion of Leptin and defining the role of AMPK in hepatic fibrosis
Tan Tan, Zhiyuan Song, Wenya Li, Runming Wang, Mingli Zhu, Zuoxiang Liang, Yilina Bai, Qi Wang, Hanyu Wu, Xiaoxiang Hu, Yiming Xing
This study creates a LEPTIN-deficient pig model of NAFLD and shows that AMPK signaling plays a key role in hepatic fibrosis progression.
Cell & Bioscience · Sep 13, 2023Peer-reviewedDevelopmental Biology