Author

Thomas Chan

Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, MA; Krantz Family Center for Cancer Research, Massachusetts General Hospital, Boston, MA; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambri;

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

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Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:scRNA-seq· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Alexandra-Chloe Villani· 1 shared Alice Tirard· 1 shared Amir T. Fathi· 1 shared Andrew M. Brunner· 1 shared Aonkon Dey· 1 shared Benjamin Arnold· 1 shared Gabriela S. Hobbs· 1 shared Hanno Hock· 1 shared

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2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alexandra-Chloe Villani

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1 paper

Recent·Most cited

Response to azacitidine and the TIM-3 inhibitor, sabatolimab, in MDS and CMML is associated with distinct immune and antigen-presentation states

Aonkon Dey, Neal Smith, Alice Tirard, Benjamin Arnold, Thomas Chan, Jennifer Lombardi-Story, Timothy Casson, Tanya T. Behnan, Sergio Aguilar-Fernandez, Amir T. Fathi, Gabriela S. Hobbs, Hanno Hock, Philip C. Amrein, Patrick Reeves, Max Jan, , Alexandra-Chloe Villani

This study identifies immune and antigen-presentation states associated with response to azacitidine and sabatolimab in MDS and CMML using single-cell RNA sequencing.

bioRxiv · Nov 5, 2026 · PreprintCancer Biology