Author

Thomas Clarke

University of Nottingham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Animal Behavior & Cognition· 1 Genetic & Genomic Medicine· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:variant calling· 2 Assay:whole-exome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Adrian Baez‐OrtegaiD· 1 shared Alex Byrne· 1 shared Alexander PayneiD· 1 shared Amy L. RobertsiD· 1 shared Andrew MahiD· 1 shared Andrew R. J. LawsoniD· 1 shared Anna PatersoniD· 1 shared Ayrun NessaiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Adrian Baez‐OrtegaORCID

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Author profile →

3 papers

Recent·Most cited

Phase response curve and RNA-sequencing demonstrate spiders' sensitivity to light and pinpoint candidate light-responsive genes

Natalia Toporikova, Wenduo Cheng, Leyuan Qian, Andrew Mah, Thomas Clarke, Thomas C. Jones, Darrell Moore, Nadia A. Ayoub

The paper uses phase response curves and RNA-sequencing to show spiders' sensitivity to light and identify candidate light-responsive genes.

PLoS ONE · Sep 23, 2026Peer-reviewedAnimal Behavior & Cognition

Somatic mutation and selection at epidemiological scale

Andrew R. J. Lawson, Federico Abascal, Pantelis A. Nicola, Stefanie V. Lensing, Amy L. Roberts, Georgios Kalantzis, Adrian Baez‐Ortega, Natalia Brzozowska, Julia S. El-Sayed Moustafa, Dovile Vaitkute, Belma Jakupovic, Ayrun Nessa, Samuel Wadge, Anna Paterson, Doris M. Rassl, , Iñigo Martincorena

The paper introduces a high-accuracy sequencing method to detect somatic mutations in tissues, revealing extensive selection and driver mutations in oral epithelium and blood samples.

medRxiv · Oct 30, 2024 · PreprintGenetic & Genomic Medicine

Nanopore adaptive sequencing for mixed samples, whole exome capture and targeted panels.

Alexander Payne, Nadine Holmes, Thomas Clarke, Rory Munro, Johnny Debebe, Matthew Loose

The paper introduces a method for targeted sequencing using nanopore adaptive sequencing, enabling efficient enrichment of specific genes and chromosomes from mixed samples.

Nature Biotechnology · Nov 30, 2020Peer-reviewedGenomics