Characterizing nascent readthrough transcripts in human cells
Ariel McShane, Ishwarya Venkata Narayanan, Michelle T Paulsen, Hailey Blinkiewicz, Mario Ashaka, Brian Magnuson, Karan Bedi, Nina Yang, Jayendra Prasad, Jefferey N Dudley, Sethuramasundaram Pitchiaya, Emily Seiden, Patrick Grohar, Erez Lieberman Aiden, Thomas E Wilson, Mats Ljungman
The paper identifies widespread readthrough transcription in human cells and shows that depletion of specific factors increases its extent.
bioRxiv · Nov 3, 2026 · PreprintMolecular Biology