Author

Timothy Lucas

University of Pennsylvania

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:scRNA-seq· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Brian L. HuangiD· 1 shared Daniel R. ConnollyiD· 1 shared Daniel Y. Zhang· 1 shared Donald M. O’RourkeiD· 1 shared E. John WherryiD· 1 shared Ernest J NelsoniD· 1 shared Fadi JacobiD· 1 shared Guo‐li MingiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Brian L. HuangORCID

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Author profile →

1 paper

Recent·Most cited

Temporal multi-modal single-cell analyses reveal dynamic interactions of CAR-T cells with glioblastoma and targeting of antigen-negative neoplastic cells

Daniel Y. Zhang, Xin Wang, Yusha Y. Sun, Qi Cui, Ernest J Nelson, Zhijian Zhang, Brian L. Huang, Josephine Ruth Giles, Radhika Thokala, Daniel R. Connolly, Fadi Jacob, E. John Wherry, Timothy Lucas, Han-Chiao Isaac Chen, Yanhong Shi, , Hongjun Song

This study uses temporal multi-modal single-cell profiling to show CAR-T cells interact dynamically with glioblastoma cells, including antigen-negative ones, and reduce their proliferation through IFN-gamma.

bioRxiv · Oct 3, 2024 · PreprintCancer Biology