Metabolic Reprogramming Driven by mpSte11A Deletion Redirects Carbon Flux toward Overproduction of Monascus Pigments in Monascus spp
Tingya Wang, Yali Duan, Yuting Liu, Mu Li
This study identifies MpSte11A as a metabolic gatekeeper in Monascus spp. that, when deleted, redirects carbon flux from primary metabolism to secondary metabolite production, resulting in a 22-fold increase in Monascus pigments.
bioRxiv · Feb 4, 2026 · PreprintMolecular Biology