Author

Travis L. Unger

University of Pennsylvania

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

Alice S. Chen‐PlotkiniD· 2 shared Marijan PosaviiD· 2 shared Alessandra ChesiiD· 1 shared Analise L. Gruenewald· 1 shared Andrew D. WellsiD· 1 shared Christopher D. BrowniD· 1 shared David A. WolkiD· 1 shared Defne A. AmadoiD· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersNeuroscience

Alice S. Chen‐PlotkinORCID

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2 papers

Recent·Most cited

TMEM106B modifies TDP-43 pathology in human ALS brain and cell-based models of TDP-43 proteinopathy

Fei Mao, John L. Robinson, Travis L. Unger, Marijan Posavi, Defne A. Amado, Lauren B. Elman, Murray Grossman, David A. Wolk, Edward B. Lee, Vivianna M. Van Deerlin, Sílvia Porta, Virginia M.‐Y. Lee, John Q. Trojanowski, Alice S. Chen‐Plotkin

This study investigates how TMEM106B and C9orf72 genetic variants influence TDP-43 pathology in ALS and FTLD-TDP, finding TMEM106B modifies TDP-43 aggregation severity.

Acta Neuropathologica · Jun 21, 2021Peer-reviewedNeuroscience

A dementia-associated risk variant near TMEM106B alters chromatin architecture and gene expression

Michael D. Gallagher, Marijan Posavi, Peng Huang, Travis L. Unger, Yosef Berlyand, Analise L. Gruenewald, Alessandra Chesi, Elisabetta Manduchi, Andrew D. Wells, Struan F.A. Grant, Gerd A. Blobel, Christopher D. Brown, Alice S. Chen‐Plotkin

The paper identifies a causal variant near TMEM106B that alters chromatin architecture and gene expression, linking it to frontotemporal lobar degeneration and neurodegenerative disease risk.

The American Journal of Human Genetics · Oct 19, 2017Peer-reviewedGenetics