Quantifying punctate morphology in mesenchymal stem cells from single cell images provides a definitive quality assessment pipeline for direct correlation to osteogenic lineage differentiation
Samikshya Purushotham, Triptish Bhattacherjee, Ayona Gupta, Samantha Shrihari, Lakshmi Balasubramanian, Urmi Bandyopadhyay, Uttara Chakraborty
The paper develops a single-cell image-based pipeline to quantify punctate morphology in MSCs and assesses its correlation with osteogenic differentiation and senescence.
bioRxiv · Oct 23, 2026 · PreprintCell Biology