Anorectal care products cause variable inflammation and adverse barrier effects in a mucosal epithelial model
Erik Swanson, Christopher M Basting, Ty Schroeder, Greg Lam, Evan Goldstein, Nichole R. Klatt
This study evaluates the effects of anorectal care products on mucosal epithelial models, finding that hyperosmolar and surfactant-containing products cause inflammation and barrier disruption, while isotonic formulations are less harmful.
bioRxiv · Nov 3, 2026 · PreprintImmunology