Author

Tyler Bryson

Genentech

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Alicja CzubatyiD· 1 shared Allen GoodmaniD· 1 shared Amy WangiD· 1 shared Andreas LoukasiD· 1 shared Andrew Leaver‐FayiD· 1 shared Andrew M. WatkinsiD· 1 shared Anna DziewulskaiD· 1 shared Anna M. SokòliD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioengineering

Alicja CzubatyORCID

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1 paper

Recent·Most cited

Lab-in-the-loop therapeutic antibody design with deep learning

Nathan C. Frey, Isidro Hötzel, Samuel Stanton, Ryan L. Kelly, Robert G. Alberstein, Emily K. Makowski, Karolis Martinkus, Daniel Berenberg, Jack J. Bevers, Tyler Bryson, Pamela Chan, Yongmei Chen, Alicja Czubaty, Tamica D’Souza, Henri Dwyer, , Vladimir Gligorijević

This paper introduces a machine learning framework for therapeutic antibody design that integrates computational methods with experimental validation, resulting in significantly improved binding affinity for multiple targets.

bioRxiv · Feb 19, 2025 · PreprintBioengineering