Continuous Production of Recombinant Adeno-Associated Virus in the Insect Cell/Baculovirus Expression Vector System
John Joseph, Francesco Destro, Arella Yuan, Daniel Antov, Wenyu Chen, Sally Song, Matthew Theriault, Chengcheng Yuan, Alexander Sansom, Chiara Lundin, Tyler Burns, Hadeel Abubaker Hamed, Piero Morales, Jessica Xinyuan Fan, Avner Romero Rodriguez, , Stacy L. Springs
This study develops a continuous production process for recombinant adeno-associated virus (rAAV) using the Sf9/BEVS system, achieving stable yields over 4 weeks.
Molecular Therapy Advances · May 1, 2026Peer-reviewedBioengineering