Mapping cis- and trans-regulatory target genes of human-specific deletions
Tyler Fair, Bryan J. Pavlovic, Dani Swope, Octavio E. Castillo, Nathan K. Schaefer, Alex A. Pollen
The paper identifies human-specific deletions that affect gene expression by using CRISPRi screening in chimpanzee stem cells.
Nature Communications · Dec 20, 2025Peer-reviewedGenetics