Mapping ortholog-restricted ligandable cysteines in the wheat pathogen Zymoseptoria tritici
Minjin Yoo, Timothy B. Ware, Sebastián Moschen, Alex Reed, Christopher J. Reinhardt, Evert Njomen, Urvashi Thacker, Bruno N. Melillo, Gabriel Scalliet, Vlad Paşcanu, Benjamin F. Cravatt
The paper identifies ortholog-restricted cysteines in Z. tritici that are targeted by stereoprobes, revealing potential fungicidal targets for combating wheat pathogens.
bioRxiv · Feb 17, 2026 · PreprintBiochemistry