Author

V. A. Spiteri

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

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A. Ciulli· 1 shared A. Kroupova· 1 shared A. Wijaya· 1 shared D. Darren· 1 shared D. Gonzales· 1 shared D. M. Lynch· 1 shared D. Zollman· 1 shared H. Furihata· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperBiochemistry

A. Ciulli

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1 paper

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedOct 15, 2024

Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders

A. Kroupova, V. A. Spiteri, H. Furihata…·A. Ciulli

The paper introduces CRBNmidi, a Cereblon construct that enables high-resolution structural and biophysical studies of degraders without requiring DDB1 co-expression.

DOI 10.1038/s41467-024-52871-9

protein structureexperimental assay