The ascorbate-deficient guinea pig model of shigellosis allows the study of the entire Shigella life cycle
A. C. Andre, C. Mulet, M. C. Anderson, L. Injarabian, A. Buck, V. M. Prade, A.-K. Walch, J. Lykkesfeldt, P. J. Sansonetti, B. S. Marteyn
This paper develops an ascorbate-deficient guinea pig model to study the full Shigella life cycle and immune responses, showing increased infection severity and prolonged bacterial dissemination.
bioRxiv · Aug 28, 2020 · PreprintMicrobiology