Vaidehi Rathi

Airway mucins function as endogenous inhibitors of neutrophil extracellular traps

This study shows that airway mucus inhibits neutrophil extracellular traps (NETs) in a sialic acid-dependent manner, and mucus dysfunction in disease can impair this regulation.

Myeloperoxidase impairs mucociliary transport on human airway epithelium

This study shows that myeloperoxidase impairs mucociliary transport in human airway epithelium by increasing airway surface liquid viscosity, similar to neutrophil elastase.

Synthetic mucus biomaterials synergize with antibiofilm agents to combat Pseudomonas aeruginosa biofilms

This study shows synthetic mucus biomaterials reduce Pseudomonas aeruginosa biofilm thickness and viability when combined with DNase and/or -amylase.