Identifying LasR quorum sensors with improved signal specificity by mapping the sequence-function landscape
Min Zeng, Biprodev Sarker, Stephen N. Rondthaler, Vanessa Vu, Lauren B. Andrews
The paper identifies highly specific LasR variants for HSL signals through mutagenesis and screening, improving signal discrimination in microbial consortia.
ACS Synthetic Biology · Jan 11, 2024Peer-reviewedSynthetic Biology