Optogenetic induction of TAD boundary pairing promotes gene activity
Martin Stortz, Murali Palangat, Veer Keizer, Raj Chari, Daniel R Larson, Tom Misteli
This study uses OptoTet to manipulate TAD boundaries and shows that boundary pairing enhances gene activity for ERRFI1 but not MYC.
bioRxiv · Nov 6, 2026 · PreprintMolecular Biology