Genomic dissection and mutation-specific target discovery for breast cancer PIK3CA hotspot mutations
Adam X. Miranda, Justin D. J. Kemp, Brad A. Davidson, Sara E. Bellomo, Verda Agan, Alexandra A Manoni, Caterina Marchiò, Sarah Croessmann, Ben Ho Park, Emily C. Hodges
The paper identifies mutation-specific targets for PIK3CA hotspot mutations using a multi-modal genomics approach and isogenic cell lines.
bioRxiv · Jan 3, 2024 · PreprintGenomics