Exploring the Antidepressant Effects of Saffron Constituents: Targeting Dopamine and Serotonin Transport Proteins, and Monoamine Oxidase-B: An in Silico Evidence-Based Study
Brijendra Bahadur Singh, Deepak sharma, Vyas Shingatgeri, Vinay Lomash
This study investigates the antidepressant potential of saffron compounds through molecular docking and pharmacokinetic analysis, finding safranal as a promising natural inhibitor of dopamine transporter with favorable BBB permeability and binding affinity.
bioRxiv · Mar 19, 2026 · PreprintNeuroscience