Skeletal muscle myosin heavy chain protein fragmentation as a potential marker of protein degradation in response to resistance training and disuse atrophy
Daniel L. Plotkin, Madison L. Mattingly, Derick A. Anglin, John Max Michel, Joshua S. Godwin, Mason C. McIntosh, Nicholas J. Kontos, João Guilherme Almeida Bergamasco, Maíra C. Scarpelli, Vitor Angleri, Lem W. Taylor, Darryn S. Willoughby, Christopher Brooks Mobley, Andreas N. Kavazis, Carlos Ugrinowitsch, , Michael D. Roberts
This study examines how resistance exercise and disuse atrophy affect myosin heavy chain (MyHC) protein fragmentation in humans, finding increased fragmentation post-exercise and during atrophy, with adaptive responses after training.
Experimental Physiology · Aug 24, 2024Peer-reviewedMolecular Biology