Pathway-guided deep neural network toward interpretable and predictive modeling of drug sensitivity
Lei Deng, Yideng Cai, Wenhao Zhang, Wenyi Yang, Bo Gao, Hui Liu
This paper introduces pathDNN, a pathway-guided deep neural network that improves interpretability and predictive performance in drug sensitivity modeling for cancer cells.
Journal of Chemical Information and Modeling · Aug 17, 2020Peer-reviewedBioinformatics