Author

Will Grathwohl

University of Toronto

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Biology Disciplines

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Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 1 Research Focus:sequence-to-function modeling· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

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Alan N. AminiD· 1 shared Daniel KassleriD· 1 shared Debora S. MarksiD· 1 shared Eli N. WeinsteiniD· 1 shared Jean DissetiD· 1 shared

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2021-2021 · peak 1/yr

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1 shared paperSynthetic Biology

Alan N. AminORCID

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1 paper

Recent·Most cited

Optimal Design of Stochastic DNA Synthesis Protocols based on Generative Sequence Models

Eli N. Weinstein, Alan N. Amin, Will Grathwohl, Daniel Kassler, Jean Disset, Debora S. Marks

The paper introduces a black-box algorithm to optimize stochastic DNA synthesis protocols for generating samples from generative sequence models, showing significant improvements in hit rates for protein engineering.

bioRxiv · Oct 28, 2021 · PreprintSynthetic Biology