Elunetirom, a brain-targeted TRβ prodrug, promotes neuronal plasticity and mitochondrial biogenesis-related signaling in primary neuronal cultures
Jason R. Harris, Jill Baccei, Will Stratton, Stephen M. Stahl, Roger S. McIntyre, Thomas S. Scanlan, Gudarz Davar
Elunetirom and LL-340001 enhance neuronal plasticity and mitochondrial biogenesis in neuronal cultures, suggesting potential for treating depression.
bioRxiv · Jul 25, 2026 · PreprintNeuroscience